2022/10/28
The gap in pharmaceutical intermediates is large
China has become the world's largest producer of antipyretic analgesics, the output of aspirin, paracetamol, metamizole and other varieties has exceeded 10,000 tons, and the output of phenacetin, aminopyrine, antipyrine and other varieties has exceeded 1000 tons. At present, the production of antipyretic analgesics in China has grown rapidly, and it is expected to increase at a rate of about 8% in the future. The output of intermediates for the supporting production of antipyretic analgesics is large, and there are many production enterprises. With the growth of antipyretic analgesics, the intermediates have also developed considerably.
2022/10/28
Production characteristics of pharmaceutical intermediates
Looking at the entire industry, the current production of pharmaceutical intermediates in China has six characteristics:
2022/10/28
Introduction to pharmaceutical intermediates
The so-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This chemical product, which does not require a drug production license, can be produced in ordinary chemical plants, as long as it reaches some level, it can be used for the synthesis of drugs.
2022/10/28
Industrial application of nano calcium carbonate
Nano calcium carbonate is used in the feed industry and can be used as a calcium supplement to increase the calcium content of feed. Used in cosmetics, due to its high purity, good whiteness and small particle size, it can partially replace titanium dioxide, and adding nano calcium carbonate to toothpaste can improve its extrusion performance. With the rapid development of China's rubber, plastics, papermaking, coatings, inks and other industries, the continuous improvement of product quality and industry standards, nano calcium carbonate will be widely used in various industries to replace imported similar products.
2022/10/28
Application range of nano calcium carbonate
Main applications: PVC profiles, pipes; Wire and cable outer skin granules; Production of PVC film (calendered film), footwear manufacturing (such as PVC soles and decorative patches), etc. Suitable for engineering plastics modification, PP, PE, PA, PC, etc. Application characteristics: Because the surface of active nano calcium carbonate is lipophilic and hydrophobic, it has good compatibility with resin, which can effectively improve or adjust the rigidity, toughness, finish and flexural strength of products; Improve the processing performance, improve the rheological properties, dimensional stability and heat stability of the product, which has the effect of filling and strengthening and toughening, which can replace some expensive fillers and aids, reduce the amount of resin, thereby reducing the production cost of products and improving market competitiveness.
2022/10/28
Production process of nano calcium carbonate
The production process of nano calcium carbonate mainly uses carbonization method, mainly including batch carbonization method, continuous spray carbonization method, hypergravity carbonization method and other production methods. The production process of heavy calcium carbonate is mainly crushing, ultra-fine crushing, grading and surface modification. The production process of light calcium carbonate generally uses limestone as raw material to prepare precipitated calcium carbonate products by calcination, digestion, carbonization, separation, drying, grading, packaging and other processes.
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